Find the next way to build molecules

innovating catalysis since 2025

Welcome to the
Lavagnino Lab

reaction discovery at cornell university

The Lavagnino Lab is advancing the frontiers of catalysis through creative reaction design, fundamental reactivity studies, and insightful mechanistic investigations.

new design principles for catalytic cross-coupling

Explore our focuses

Underutilized catalytic centers

By integrating novel bond-forming steps, we extend cross-coupling chemistry beyond the d‑block

Elusive coupling partners

Controlled crossover of reactive intermediates enables us to activate desired feedstocks in chemical processes

Unconventional cycle design

We pursue reaction generality by applying fundamentally distinct selectivity principles to cross-coupling

hot off the presses

The latest results

The Lavagnino Lab’s focus is catalysis, or how to lower the energy barriers of challenging–yet enabling–chemical transformations. By applying the techniques of organic reaction development, organometallic synthesis, and physical organic investigation, we aim to discover reactivities that empower chemists to build the molecules needed by the modern world.

interdisciplinary excellence

The people who make it happen

Brought together by a shared passion for pushing the frontiers of synthetic chemistry, members of the group are driven individuals who bring their unique experiences, interests, and talents to the table.